In bioreactor systems, optimal mass transfer of gases like oxygen or carbon dioxide is difficult to accomplish. Oxygen, in particular, is poorly soluble in water – and even less in cell culture and fermentation broths. Oxygen transfer is aided by agitation used to mix nutrients and to keep the cell culture or fermentation homogeneous. There are limits to agitation speed due to high power consumption as well as damage to organisms resulting from excessive tip speed. Agitation alone does not provide adequate mass transfer. Using a Mott porous metal sparger greatly increases mass transfer rates in this equipment. The introduction of gases into stirred or unstirred reactor vessels via millions of tiny bubbles increases the gas-to-liquid contact areas allowing for optimal mass transfer rates.
Mott spargers increase gas absorption in various processes by 300-500% over drilled pipe.
- Gas injection to enhance cell growth
- Gas injection for reaction and mixing
- Chemical Processing